There is nothing to configure manually on a Pi, but you have to make sure that it is on the same network as your main computer running the software.
Make sure that all Pis are running the same image version
Your firewall might be preventing Xangle from seeing your Pis. Try to disable it momentarily to diagnose. If you're using McAfee, you can let Xangle going through by doing this:
https://xangle.zendesk.com/hc/article_attachments/11399749761684
A Raspberry Pi rarely fails, but a micro-sd card can easily get corrupted. It is a good idea to have a few spare cards nearby in case this happens.
If your main computer has more than one network interface (typically with a network cable and a wifi connection), you might have to select the right one. You can change network interface straight from the dashboard
From the server, you can get a list of the connected Raspberry Pis by either looking at the DHCP client list from your router settings, or, you can install MobaXterm (check in Tools / Network scanner
From the Pi, there's a way to see the ip address of the Pi by connecting a monitor to its hdmi port. This is going to give you this display: